Implementation of the paper - Generative Recurrent Networks for De Novo Drug Design.

SIRIUS is a software for discovering a landscape of de-novo identification of metabolites using tandem mass spectrometry. This repository contains the code of the SIRIUS Software (GUI and CLI)

Long short-term memory recurrent neural networks for learning peptide and protein sequences to later design new, similar examples.

This is the codebase for Recycler, described in our manuscript: https://academic.oup.com/bioinformatics/article/33/4/475/2623362, by Roye Rozov, Aya Brown Kav, David Bogumil, Naama Shterzer, Eran Halperin, Itzhak Mizrahi, and Ron Shamir

Simple bacterial assembly and annotation pipeline

sirius-libs - Metabolomics mass spectrometry framework for molecular formula identification of small molecules written in Java

Preforms De novo protein design using machine learning and PyRosetta to generate a novel protein structure

Implementation of the paper - Automatic chemical design using a data-driven continuous representation of molecules

HAT is a set of tools for calling de novo variants from whole-genome sequencing data.

Graphical user interface for de novo sequencing of tandem mass spectra

A bare metal Python library for building and manipulating protein molecular structures

UNDER CONSTRUCTION: Hybrid genome assembly pipeline using a combination of long and short sequencing reads

A de novo variant caller leveraging Parabricks GPU accelerated variant calling

acorn is an R package that examines various features of de novo variants including subsetting DNVs by individual, variant type, or genomic region; calculating features including variant change counts, lengths, and presence/absence at CpG sites; and characteristics of parental age and number of DNVs.

Tortoise is the CPU workflow of the HAT https://github.com/TNTurnerLab/HAT tools.

HARE is the GPU workflow of the HAT https://github.com/TNTurnerLab/HAT tools.

Statistical models for finding de novo recurrence and compound heterozygosity across rare disease patient cohorts

A fast and accurate tool that identifies Mendelian violations in family trios. Resolve variant representation issues in VCF files

De novo identification of LTR retrotransposons