A simple approach to achieving high accuracy in isothermal titration calorimetry (ITC) measurements
This project provides simple guidelines for making accurate measurements of biomolecular association using isothermal titration calorimetry (ITC), and worksheets for easily propagating error in solution concentrations and data fitting.
Boyce SB, Tellinghuisen JT, and Chodera JD. Avoiding accuracy-limiting pitfalls in the study of protein-ligand interactions with isothermal titration calorimetry. bioRxiv
worksheets/
- spreadsheets for preparing and analyzing ITC experiments (in multiple formats)manuscript/
- LaTeX manuscript source for the paperdata/
- data used in the paperreferences/
- some useful references cited in the paper