[WIP] Add example sequential titration assay data

[jchodera]

This PR adds some preliminary analysis of sequential titration assay data from @MehtapIsik.

We may not want to add all of this data, but it may be easier than trying to extract some partial data.

This Jupyter notebook contains some exploratory data analysis and should be useful in feeding the data to assaytools for fitting binding affinities.

[Lucelenie]

@MehtapIsik @steven-albanese I tried to plot the data from the sequential titration test that I ran last week. You can find notebook here. Also, here is the layout with the p38, buffer and p38 boiled samples:

[MehtapIsik]

@Lucelenie I have just realized well H12 in your plate layout has protein. It is not just containing buffer. That can explain why H12 (dispense priming well for D300) doesn't have a linear fluorescence increase.

[jchodera]

Hm. The data looks like there isn't really a binding signal of any sort in there.
Which ligand(s) did you use?

[Lucelenie]

Bosutinib

[steven-albanese]

We think there might have been an issue with dispensing the ligand. We're going to make a new stock of bosutinib and redesign the experiment a bit

[steven-albanese]

@Lucelenie doesn't think this was an issue this run, but I'm also concerned that there's a problem with the infinite, which has been having trouble reading

[Lucelenie]

I found out that I made a mistake when placing the stock plate on the EVO. Because of this mistake, bosutinib wasn't dispensed. I will run this test again.

[Lucelenie]

@MehtapIsik @steven-albanese
Here is the plate layout for the latest test experiment. Also, you can find a notebook of the data here.

[jchodera]

Should this branch be merged?