Averaged Neuron (AN) model

Overview

AN model is a conductance-based (Hodgkin-Huxley type) neuron model using the mean-field approximation of groups of neurons. The model can recapitulate the slow-wave sleep (SWS) firing pattern and the sleep spindle (SS) firing pattern.

Dependencies

The following packages need to be installed to use AN model:

• Python >= 3.5
• Numpy >= 1.10
• Scipy >= 1.0.0

Usage (plotting the SWS firing pattern)

import matplotlib.pyplot as plt
import anmodel
an = anmodel.models.ANmodel()
an.set_sws_params()
s, _ = an.run_odeint()
plt.plot(s[4999:, 0])

References

SWS (slow-wave sleep) firing pattern

• Tatsuki et al., Neuron, 2016
• Rasmussen et al., Cell Systems, 2017
• Yoshida et al., PNAS, 2018

SS (sleep spindle) firing pattern

• Yamada et al., iScience, 2021

License

This project is licensed under the MIT License - see the LICENSE.txt file for details.