acid base reaction smarts #7284
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manajit-das
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Hello, though I can write reaction SMARTS for simple reactions, the acid base reactions involving H atoms seems tricky to me. Here is what I would like to have: a base abstracting a proton from a neutral amine or cationic ammonium ion (see Figure)?
![AcidBase](https://private-user-images.githubusercontent.com/59758360/315301829-5f0f6419-86a7-4450-9146-bb530edf8066.PNG?jwt=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.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.U1CyLESgbur3WCw9G8FJI-mNRzkaPkP9IZyUvVAZ8-0)
I have tried the following, but it failed which I assume because of improper handling of H atoms, any solutions will be very helpful. Thank you.
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