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mccortex subgraph behaviour #87

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izaak-coleman opened this issue Aug 15, 2019 · 0 comments
Open

mccortex subgraph behaviour #87

izaak-coleman opened this issue Aug 15, 2019 · 0 comments

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@izaak-coleman
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I have a couple of questions about the behaviour of mccortex31 subgraph.

Firstly, does --dist d specify the radius or diameter? i.e will subgraph extend from the input sequence a distance of d to the left and right (--dist specifies radius) or a distance of d/2 to the left and right (--dist specifies diameter)?

Secondly, if the sequence passed to --seq is a single kmer (of len 31 in this case), and
distance passed to --dist is d, if --dist specifies radius, is it the case that the maximum number of possible kmers that could be pulled from the original graph is4^d + 4^d + 1 (one 4^d term each for left and right extension, 1 for the original seed kmer) assuming each node in the de brujin graph has four edges?

Finally, if the sequence passed to --seq contains multiple uncontiguous kmers, will each of the kmers be extended a distance of d?

Kind regards, and thanks for any insight given!
Izaak Coleman

@izaak-coleman izaak-coleman changed the title mccortex subgraph behaviour mccortex subgraph behaviour label:question Aug 15, 2019
@izaak-coleman izaak-coleman changed the title mccortex subgraph behaviour label:question mccortex subgraph behaviour Aug 15, 2019
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