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Naive questions #83

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brianlamx opened this issue Jan 23, 2020 · 0 comments

brianlamx commented Jan 23, 2020

Dear Jean (and Peter),

I'm new to the scde and I'm still working through the tutorial. I have 2 very naive questions and would appreciate if you could enlighten me:

is it normal to see genes that have exactly the same MLEs (and even CIs)? I see blocks of genes that share the same values over and over again.
why is the mle different when you look at the full transcriptome vs single gene? I notice this in the tutorial: for Tdh the mle is 8.03544 alone and 8.075220 in ediff.

Many thanks
Brian

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