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Perform additional analysis for genes / shared genes #29

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apriha opened this issue Apr 15, 2018 · 0 comments
Open

Perform additional analysis for genes / shared genes #29

apriha opened this issue Apr 15, 2018 · 0 comments

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@apriha
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apriha commented Apr 15, 2018

General Gene Analysis

  • Group genes by transcripts
  • Link to gene information (e.g., NCBI, OMIM, etc.) (see #12 and Add plotting capabilities #22)
  • Indicate if gene is susceptible to CNV (see Add plotting capabilities #22)
  • Identify genomic regions possibly related to gene regulation and susceptible to methylation (e.g., CpG islands)
  • For SNPs in coding regions, identify effect of SNP on amino acid produced compared to reference sequence (i.e., whether variation results in a change of amino acid)

Shared Genes

  • Identify genes partially shared (i.e., gene overlaps shared DNA segment)
  • Identify percentages of coding / non-coding regions shared
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